The Peptide Oxytocin Antagonist F-792, When Given Systemically, Does Not Act Centrally in Lactating Rats
نویسندگان
چکیده
منابع مشابه
The Peptide Oxytocin Antagonist F‐792, When Given Systemically, Does Not Act Centrally in Lactating Rats
Prenatal stress (PNS) affects a number of traits in the offspring, including stress axis regulation, emotionality and cognition; however, much less is known about the effects of PNS on social memory and the underlying central mechanisms. In the present study, we investigated social preference, social memory under basal and stress conditions and olfactory memory for social and nonsocial odours i...
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Sexual activity and mating are accompanied by a high level of arousal, whereas anecdotal and experimental evidence demonstrate that sedation and calmness are common phenomena in the postcoital period in humans. These remarkable behavioral consequences of sexual activity contribute to a general feeling of well being, but underlying neurobiological mechanisms are largely unknown. Here, we demonst...
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We examined the effects of intracerebroventricular (i.c.v.) administration of adrenomedullin 2 (AM2) on plasma oxytocin (OXT) and arginine vasopressin (AVP) levels in conscious rats. Plasma OXT levels were markedly increased 5 min after i.c.v. administration of AM2 (1 nmol/rat) compared with vehicle and remained elevated in samples taken at 10, 15, 30, and 60 min. By contrast, plasma AVP levels...
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We examined the effects of i.c.v. administration of adrenomedullin 5 (AM5) on the brain of conscious rats. We used porcine AM5 in the present study because rat AM5 has not been detected. We observed Fos-like immunoreactivity (LI) in the hypothalamus and brainstem of conscious rats after i.c.v. administration of AM5 (2 nmol/rat). Fos-LI, measured at 90 min post-AM5 injection, was observed in var...
متن کاملF-regularity Does Not Deform
We show that the property of F-regularity does not deform, and thereby settle a longstanding open question in the theory of tight closure. Specifically, we construct a three dimensional N-graded domain R which is not F-regular (or even F-pure), but has a quotient R=tR which is F-regular. Examples are constructed over fields of characteristic p > 0, as well as over fields of characteristic zero.
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ژورنال
عنوان ژورنال: Journal of Neuroendocrinology
سال: 2016
ISSN: 0953-8194
DOI: 10.1111/jne.12331